Table 6

Study Characteristics of Selected Experimental Controlled Anima Studies on He-Ne Low Level Laser Irradiation Effects on Bone Healing

Authors

Laser Output

(mw)

Distance between Producer and Skin

(cm)

Irradiation Time per Day

(min)

Number of treatment sessions

Irradiated energy per session

Total Irradiated Energy

David et al., 1996

10

N/A

N/A

2 week

4 week

6 week

(2 week) 6

0

0

0

0

(4 week) 13

2

12

26

40

(6 week) 20

4

(J) every other day

24

52

(Joules)

80

Luger et al., 1998

35

20

**

30

14

***

***

21 J (each area)

294 (J) (each area)

63 J (in total)

882 (J) (in total)

Tajali et al., 2003

2

N/A

**

30

14

1.2 (J/cm2)

16.8 (J/cm2) ***

21

5.2 (J/cm2)

28

33.6 (J/cm2)

Teng

et al.,

2006

N/A

N/A

10

35

***

***

He-Ne: 16.8 (J/cm2)

He - Ne: 588 (J/cm2)

Co2: 90 (J/cm2)

Co2: 3150 (J/cm2)

** Including 10 minutes on fracture area, 10 minutes on the area above the point of fracture, and 10 minutes on the area below the fracture. *** Meta analysis authors calculated amount of irradiated energy based on the articles data with this equation [43]:

Set Power (w) * Time (s) = Total Amount of Energy (J)

Total Amount of Energy/Treatment Surface (cm2) = Energy Density (J/cm2)

Bashardoust Tajali et al. Journal of Orthopaedic Surgery and Research 2010 5:1   doi:10.1186/1749-799X-5-1