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Effect of combined treatment with alendronate and calcitriol on femoral neck strength in osteopenic rats

Yoshinari Nakamura1 email, Masatoshi Naito1 email, Kazuo Hayashi2 email, Abbas Fotovati2 email and Samah Abu-Ali2 email

Department of Orthopaedic Surgery, Fukuoka University School of Medicine, Fukuoka, Japan

Rheumatology and Arthritis Center Fukuoka Wajiro Hospital 2-2-75, Wajirooka, Higashi-ku, Fukuoka, Japan

author email corresponding author email

Journal of Orthopaedic Surgery and Research 2008, 3:51doi:10.1186/1749-799X-3-51

Published: 17 December 2008

Additional files

Additional file 1:

Relation between bone mass parameters and fracture load at the femoral neck. In all groups, there were significant correlations between the fracture load and total BMC, cortical BMC or total bone area at the femoral neck. In all groups, the alendronate-treated groups (ALN and ALN + Vit.D), the calcitriol-treated groups (Vit.D and ALN + Vit.D) and combined treatment group, there were significant correlation between the fracture load and total BMC in the femoral neck.

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