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Definition of the histological types of periprosthetic membranes (Krenn and Morawietz et al.) |
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| Type |
Characteristics |
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| Type I – Periprosthetic membrane of the wear particle induced type |
Infiltration of predominantly macrophages and multinuclear giant cells containing PE particles |
| Type II – Periprosthetic membrane of the infectious type |
Activated fibroblasts, proliferation of small blood vessels, oedema, and inflammatory infiltrate of neutrophilic granulocytes |
| Type III – Periprosthetic membrane of the combined type |
Combination of the histomorphological changes described for types I and II |
| Type IV – Periprosthetic membrane of the indeterminate type (non infected, non wear particle induced) |
Connective tissue low in cells and rich in collagen fibres |
Müller et al. Journal of Orthopaedic Surgery and Research 2008 3:31 doi:10.1186/1749-799X-3-31 |
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