Table 1

Definition of the histological types of periprosthetic membranes (Krenn and Morawietz et al.)

Type
Characteristics

Type I – Periprosthetic membrane of the wear particle induced type
Infiltration of predominantly macrophages and multinuclear giant cells containing PE particles
Type II – Periprosthetic membrane of the infectious type
Activated fibroblasts, proliferation of small blood vessels, oedema, and inflammatory infiltrate of neutrophilic granulocytes
Type III – Periprosthetic membrane of the combined type
Combination of the histomorphological changes described for types I and II
Type IV – Periprosthetic membrane of the indeterminate type (non infected, non wear particle induced)
Connective tissue low in cells and rich in collagen fibres

Müller et al. Journal of Orthopaedic Surgery and Research 2008 3:31   doi:10.1186/1749-799X-3-31

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